2025 American Society of Microbiology ABMM: Marvelous Reliable ABMM Exam Test
2025 American Society of Microbiology ABMM: Marvelous Reliable ABMM Exam Test
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American Society of Microbiology ABMM Sample Questions (Q147-Q152):
NEW QUESTION # 147
A clinical microbiology laboratory is performing antimicrobial susceptibility testing on a Streptococcus pneumoniae isolate recovered from a patient with meningitis. The isolate shows reduced susceptibility to penicillin (MIC = 2 µg/mL). The MOST likely mechanism for this reduced susceptibility is:
- A. Increased activity of efflux pumps that actively remove penicillin from the cell.
- B. Production of beta-lactamase enzymes that hydrolyze penicillin.
- C. Alterations in the penicillin-binding proteins (PBPs) that reduce their affinity for penicillin.
- D. Modification of the peptidoglycan structure, preventing penicillin binding.
Answer: C
NEW QUESTION # 148
A clinical microbiology laboratory is investigating a cluster of bloodstream infections caused by Staphylococcus aureus. To differentiate between community-associated (CA-MRSA) and healthcare- associated (HA-MRSA) strains, they may look for the presence of:
- A. Specific staphylococcal cassette chromosome mec (SCCmec) types, such as SCCmec IV or V inCA- MRSA.
- B. Panton-Valentine leukocidin (PVL) toxin genes, which are exclusively found in HA-MRSA.
- C. The mecA gene, which is common to both CA-MRSA and HA-MRSA.
- D. Resistance to non-beta-lactam antibiotics, which is more common in CA-MRSA.
Answer: A
NEW QUESTION # 149
A microbiology laboratory is processing a stool sample for ova and parasites. A large (approximately 100
µm), thick-shelled, oval egg with a flattened side is observed. This egg MOST likely belongs to:
- A. Taenia species
- B. Enterobius vermicularis
- C. Trichuris trichiura
- D. Ascaris lumbricoides
Answer: D
NEW QUESTION # 150
A 55-year-old male with a history of poorly controlled diabetes mellitus develops a necrotizing fasciitis of his left lower extremity following a minor abrasion sustained while gardening. Initialcultures of the wound reveal a polymicrobial flora, including Gram-positive cocci in chains and Gram-negative bacilli. Over the next 48 hours, despite broad-spectrum antibiotic therapy, the patient's condition deteriorates, and new bullae with hemorrhagic fluid appear. Gram stain of this fluid now predominantly shows large, Gram-positive bacilli with subterminal spores. Which of the following virulence factors is MOST likely contributing to the rapid tissue destruction observed in this patient?
- A. Lecithinase (alpha-toxin)
- B. Lipopolysaccharide (LPS)
- C. Protein A
- D. Exotoxin B (SpeB)
Answer: A
NEW QUESTION # 151
A clinical microbiology laboratory is implementing a new laboratory information system (LIS). A critical step in the validation process is ensuring the accurate and reliable transfer of data, including patient demographics, test orders, and results. This aspect of validation primarily focuses on:
- A. Analytical sensitivity and specificity.
- B. Data integrity and interoperability.
- C. Clinical sensitivity and specificity.
- D. Workflow efficiency and user training.
Answer: B
NEW QUESTION # 152
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